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Some options marketed in wellness spaces are still emerging, and quality can vary

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When to seek medical advice: Patients taking GLP-1 medications should contact their GP or prescribing clinician if they experience persistent nausea affecting nutritional intake, signs of hypoglycaemia (if taking alongside other diabetes medications), severe abdominal pain (especially if radiating to the back, which may indicate pancreatitis), or any concerns about their response to treatment

Especially for patients who have fear or discomfort with injections, they may not be willing to undergo regular injections
As illustrated in Figure 1, proteolytic cleavage occurs upon processing inside the cell
