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As a result, new indications for weight management have emerged: for example, liraglutide (Saxenda) and semaglutide (Wegovy) are FDA-approved for chronic weight control, often at higher doses

To determine if this is the most appropriate treatment, pharmacists should consider the following: Administration burden: Include frequency of use and timing with meals

This occurs through two main pathways: (1) FXR induces a small heterodimer partner that represses CYP7A1 and CYP8B1 by inhibiting hepatocyte nuclear factor 4 and liver receptor homolog 1

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Semaglutide (Wegovy) Wegovy has been one of the most widely prescribed weight-loss injections worldwide since its UK launch

Semaglutide activates the GLP-1 pathway, which plays a major role in hunger signals, fullness cues, and insulin release