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In brain centers, LepRs were found in GLP-1Rexpressing neurons in the nucleus of the solitary tract and leptin was found to stimulate these neurons (113, 114)

Several studies have noted levels of homocysteine, an independent cardiovascular risk factor, are elevated in PCOS patients

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[DOI] [PMC free article] [PubMed] [Google Scholar] 15.Spring B, Duncan JM, Janke EA, Kozak AT, McFadden HG, DeMott A, Pictor A, Epstein LH, Siddique J, Pellegrini CA, Buscemi J, Hedeker D