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J Clin Invest 2002;109:112531

Several non-invasive approaches have been developed in the past for insulin delivery [212, 213], but many of these products, particularly oral insulin products, faced challenges in clinical trials due to variable therapeutic responses owing to patient-to-patient differences in bioavailability [214-216]

We further demonstrate that specifically reducing the secretion of COL IV by the niche significantly reduces GLP-1/Notch activation, establishing this relationship as causal

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Semaglutide promotes the transition of microglia from M1 to M2 type to reduce brain inflammation in APP/PS1/tau mice