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CTD is often associated with early-onset atherosclerosis and cardiovascular disease that cannot be explained by conventional risk factors

While semaglutide is deemed safe in general, caution is advised in subjects with elevated risk or history of thyroid cancer, biliary disease, renal failure, pancreatitis, and diabetic retinopathy, Furthermore, due to the increased risk of hyperglycemia, combined use of semaglutide alongside other diabetic treatments must be conducted under close supervision [16]

Plaque rupture leads to formation of a blood clot that can block blood flow or break off into circulation and obstruct smaller vessels, sometimes resulting in major, life-threatening, catastrophic cardiovascular events

We all get annoyed and even discouraged sometimes when, in spite of our best efforts, specific points remain the same

doi: 10.1136/gut.51.6.849

Prior to Mirena IUD insertion, every woman must be adequately counseled in the language she understands about the advantages, drawbacks, reversibility, precautions and safety with use of the device