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Frias, M.A

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A systematic review in effects of glucagon-like peptide-1 (GLP-1) mono-agonists on functional connectivity: target engagement and rationale for the development in mental disorders

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Almudena Castro has consulting fees from Astra Zeneca, Novartis, Boehringer-Ingelheim, Lilly, Novo-Nordisk, Bayer, Pfizer, Amgen, Sanofi, Organon, Daichii Sankyo and Vifor Pharma

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Compared to the use of GLP1-RAs alone, the combination of SGLT2is and GLP1-RAs was associated with a 30% reduction in the risk of MACE, with rates of 7.0 versus 10.3 events per 1000 person-years (HR 0.70

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In addition, it was demonstrated that yerba mat produced additional LDL-C lowering in hypercholesterolemic subjects who were on stable statin therapy, which may reduce the risk for cardiovascular diseases (Table 1)

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