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Not all of the GLP-1 agonists are great at reducing weight

Effects of GLP-1 on the Energy Balance As previously introduced, GLP-1 is a peptide released in response to nutrient ingestion by the L-cells of the gastrointestinal tract, mainly located in the distal small intestine and colon [49,50], and by the nucleus of the solitary tract [51]

Concerns could include underdosing, lack of clinical data on microdosing, and patients making decisions without guidance, Tebra researchers concluded

doi: 10.1152/ajprenal.1998.275.4.F565
The lin-12 locus specifies cell fates in Caenorhabditis elegans

doi: 10.1210/jc.2005-2220
