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Initial workup may include A1c/glucose, vitamin B12, thyroid function, and comprehensive metabolic panel

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A subsequent trial in patients with type 2 diabetes showed somewhat lower but still clinically meaningful weight reduction

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EU approves Novo Nordisks oral semaglutide owenhaskins Sep 15, 2025 2 min read The European Medicines Agencys (EMA) Committee for Medicinal Products for Human Use (CHMP) has approved an update to Novo Nordisks Rybelsus (oral semaglutide) label to reflect the cardiovascular benefits seen in the SOUL trial

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Regular heart rate monitoring during treatment is essential

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