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A pivotal 2021 clinical study of more than 1,900 adults, known as the STEP 1 trial, laid the groundwork for the use of these drugs as a treatment for weight loss

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Decreases Glucagon: Reduces production of glucagon, a hormone that raises blood sugar, preventing unnecessary glucose release from the liver

25 Changing GIP Ile 17 to Ala massively lowered the insulinotropic effect

Key Insight: Discover how GLP1 drugs may dampen alcohol cravings via brain reward pathways
