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References Tackling tolerability: The next challenge facing obesity therapies

Some evidence suggests GLP-1 might also affect reward pathways in the brain related to food cravings and the pleasure response to eating

4 Still, this research shows what happens when you stop the medications suddenly without a gradual decrease in dose (a taper), and with adequate lifestyle support alongside it

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Participants with HbA1c level ranging from 7%11% were randomized to receive daily liraglutide (1.8 mg) after a titration period of once-weekly liraglutide (0.6 mg), once-weekly (1.2 mg) for 2 weeks, or 5 g of exenatide twice daily for 4 weeks

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