glp-1 r GLP1 receptor mutations in humans affect metabolic control and modify the effectiveness of GLP1 receptor-based treatments against type 2 diabetes and obesity Frontiers | GLP−1 receptor agonists

Weight loss, particularly when gradual, can improve insulin sensitivity and help stabilize hormones like testosterone and estrogen

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Given that cessation of treatment often leads to significant weight regain, there are concerns that older adults may be at risk for sarcopenic obesity

Final supervision: J.L.G

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Scirica BM, Bhatt DL, Braunwald E, Steg PG, Davidson J, Hirshberg B, Ohman P, Frederich R, Wiviott SD, Hoffman EB, Cavender MA, Udell JA, Desai NR, Mosenzon O, McGuire DK, Ray KK, Leiter LA, Raz I: SAVOR-TIMI 53 Steering Committee and Investigators