efficacy of semaglutide and safety once-weekly monotherapy versus placebo in patients with type 2 diabetes (SUSTAIN 1): a double-blind, randomised, placebo-controlled, parallel-group, multinational, multicentre phase 3a trial How Long Has Semaglutide Been
Description
These findings demonstrate sex-specific effects of semaglutide, highlighting the need to consider biological sex in GLP-1RAbased therapies

However, it appears that if people taking the drugs stop, most regain the weight they lost and the health problems that come with weight gain
Impact of GLP-1 receptor agonists on suicide behavior: a meta-analysis based on randomized controlled trials
Abstract Aims/hypothesis: Intra-abdominal or visceral obesity is associated with insulin resistance and an increased risk for cardiovascular disease

According to Reuters, a number of smaller companies, including Neuraly and Kariya Pharmaceuticals, have said they are evaluating the effects of needles of their experimental GLP-1 drugs in Parkinson's disease and are considering expanding the study area to Alzheimer's disease after results from the Novo Nordisk trial

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