glp-1 weight loss drug news today drugs like Ozempic linked to slower cancer spread, study finds New GLP-1 alternative, eloralintide, leads

The prescribing information for these medications contains a boxed warning regarding the potential risk of thyroid C-cell tumors, a rare form of thyroid cancer

Other New Stuff: The Genetics of G-Agonists In a seminal study of the genomics of glucose regulation in nearly 500,000 people, specific coding variants of the GLP-1 receptor (GLP1R) were associated with potential GLP-1 drug response

ESC The ESC guidelines recommend the use of GLP-1 RAs in overweight or obese patients with T2DM to promote weight reduction (Class IIa, LoE B)

Wegovy generally produces roughly twice as much average weight loss as Saxenda based on trial data

While semaglutide is generally well tolerated, it is most commonly associated with gastrointestinal symptoms such as nausea or diarrhea, especially during the early stages of treatment or when the dose is increased

They regulate blood sugar and appetite by mimicking the action of the naturally occurring gut hormone GLP-1, a modulator of insulin secretion, glucagon, stomach emptying, and satiety signalling