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Here, we review the pharmacokinetics, pharmacokinetic drugdrug interactions (DDIs), and pharmacokinetic modeling approaches of four currently available GLP-1 RAs (exenatide, liraglutide, dulaglutide, and semaglutide) and tirzepatide

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Clinical perspectives on the use of the GIP/GLP-1 receptor agonist tirzepatide for the treatment of type-2 diabetes and obesity - Frontiers in Endocrinology Semaglutide vs Tirzepatide for Weight Loss in Adults With Overweight or Obesity - JAMA Internal Medicine Tirzepatide versus Semaglutide Once Weekly in Patients with Type 2 Diabetes - New England Journal of Medicine Tirzepatide for Diabetes Improves Glycemic Control After Switch From GLP-1RA - Endocrinology Advisor Weight regain and cardiometabolic effects after withdrawal of semaglutide: The STEP 1 trial extension - Diabetes, Obesity and Metabolism