eli lilly glp 1 pipeline GLP-1 2.0: Where the Next Wave of Value Will Be Created GLP-1 Pipeline graphic : r/Zepbound
Description
84.6% of patients achieved more than 5% weight loss compared to 25% on lifestyle changes alone

Judge Marson also presides over the GLP-1 MDL that focuses on gastrointestinal injuries
This first wave of GLP-1s were commercially successful (Victoza saw peak sales of ~$3.8B in 2018), but results were modest relative to todays market
The first generation of GLP-1 RAs typically induces a 510% weight loss, whereas the newest more potent generation, semaglutide 2.4 mg once weekly, has demonstrated a 1516% weight loss (Wadden et al

The ACCC declined to comment.

J Gastrointest Surg
