glp 1 and bowel obstruction Adverse effects of GLP-1 class drugs. Gastrointestinal issues are Fixing GLP-1 Constipation
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USA 107, 1305762 (2010)

GLP-1 (glucagon-like peptide-1) plays a role in regulating blood sugar, enhancing insulin secretion, slowing gastric emptying, and promoting feelings of fullness

The science here is not speculative

N Engl J Med 292(19):9859 Ghimire P, Dhamoon AS (2023) Ketoacidosis

The FTO rs9939609 variant is linked to baseline hunger drive and metabolic rate

GLP1 receptor agonists for the treatment of obesity: role as a promising approach
