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A weight regain of 11.6% in the semaglutide group and 1.9% in the placebo

[DOI] [PubMed] [Google Scholar] 29.Britsch S, Krippeit-Drews P, Lang F, Gregor M, Drews G

A safety profile consistent with extensive experience in diabetes and obesity

In murine pancreatic Min6-K8 cells, prevention of cytosolic glutamate production by KO of a key component of the malate-aspartate shuttle or triple KO of the vesicular glutamate transporters Slc17a6, Slc17a7, and Slc17a8 impaired GLP-1-induced insulin secretion [515]
