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Randomized, double-blind, phase 3 trial of triple therapy with dapagliflozin add-on to saxagliptin plus metformin in type 2 diabetes

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Drink plenty of water Regular fluid intake prevents dehydration, reducing the risk of constipation

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Mood symptoms Animal studies, case reports, and a meta-analysis of RCTs of GLP-1 RAs suggest that these medications might help with depression (Chen X et al, Am J Geriatr Psychiatry 2024;32(1):117127)

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