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For patients using insulin or sulfonylureas, reducing their doses by 25% when starting GLP-1 therapy can help avoid hypoglycemia

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Frequent vomiting, persistent nausea, or inability to maintain normal food intake should always be evaluated

Some patients may begin noticing weight loss within the first few weeks, especially when medication is paired with lifestyle changes

TGF-1 + IL-1 significantly boosted mitochondrial respiration, including basal respiration, maximal respiration and ATP-linked respiration in fibroblasts (Fig

Lixisenatide reduces postprandial hyperglycaemia via gastrostatic and insulinotropic effects