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In humans, diastolic dysfunction results from structural and functional changes that increasingly impede diastolic filling after midlife

Hold the pen in place for at least 6 seconds to ensure the full dose is delivered

This suggests that the GLP-1R KO mouse model may serve as a model for correlated metabolic and functional connectivity loss.

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Outcomes included changes in left ventricular ejection fraction (LVEF), end-diastolic volume (LVEDV), end-systolic volume (LVESV), global longitudinal strain (GLS), left ventricular mass, left atrial volume (LAV), and NT-proBNP levels

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