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There is direct evidence comparing semaglutide to sitagliptin and dulaglutide in patients inadequately controlled on one oral antidiabetic drug (OAD), and to exenatide or insulin glargine in patients with inadequate glycemic control with one or two OADs, however data are lacking for other comparators

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GLP-1 medications like Wegovy and Zepbound can produce 1522% body weight loss

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