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Such models do not adequately reflect the heterogeneity of human SUD populations, which differ in sex, age, comorbidities, and environmental context

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Non-coding RNA modifications Non-coding RNAs, including miRNAs, small interfering RNAs (siRNAs), and long non-coding RNAs (lncRNAs), also play critical roles in regulating gene expression during spermatogenesis

[DOI] [PMC free article] [PubMed] [Google Scholar] 24.Bittner B, McIntyre C, Jordan P, Schmidt J

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The altered homeostatic incretin levels in PAR2-G37I or PAR2-R38E versus WT mice were not caused by apparent changes in metabolism, as no significant differences in food and fluid intake, energy expenditure, respiratory exchange ratio, or locomotor activity were observed in indirect calorimetry (Supplemental Figure 2, A and B)