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(18) described a change toward a less inflammatory state in animals treated with GLP-1 receptor agonists

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Important safety information: Mounjaro (tirzepatide) and Wegovy (semaglutide) are prescription-only medications for managing obesity

They also decrease the release of IL-33 through which inflammatory Th2 are reduced and IL-5 and 13 are released, leading to a reduced number of eosinophils and reduced goblet metaplasia and mucus production (Figure 2) [53]

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In addition to greatly reducing HbA1c levels, tirzepatide treatment was not associated with increased cardiovascular risk [7, 26]