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Zepbound (tirzepatide) is an FDA approved weight loss medication that targets both GLP-1 and GIP receptors

The treatment usually begins with a low dose to allow the body to adjust gradually, optimizing results over time and minimizing potential adverse reactions

In adipocytes, caveolin-1 plays a role in the insulin transduction pathway by modulating the activity of down-stream signaling proteins including Akt (94), raising the possibility that DPP-4 may be able to influence adipocyte insulin sensitivity by modulating the activity of caveolin-1 (Figure 3)

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