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We now have a NICE-funded route to semaglutide 2.4 mg for secondary CV prevention, alongside standard care, a reduced-calorie diet and increased physical activity, and not dependent on diabetes or Tier 3 weight-management eligibility

Stronger inverse associations were seen among older men (70 years) (ITT HR 0.56

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Most people notice appetite changes within two to four weeks of starting semaglutide, with meaningful weight loss appearing between weeks 6 and 12
