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Some peptides, like Semaglutide and Tirzepatide, reduce appetite and control blood sugar, making them suitable for individuals with obesity or diabetes

Leptin, produced by fat cells, tells your brain you have adequate energy stores

Hoffmann-La Roche Ltd was involved in the study design, collection, analysis, interpretation of data, the writing of this article and the decision to submit it for publication

Against this background, in 2019 liraglutide became the first GLP-1 analogue approved by the FDA, EMA and MHRA as a treatment option for obesity (65)

Boxed warning (applies to the drug class): In animal studies, GLP-1 receptor agonist medications caused thyroid tumors, including thyroid cancer

Reducing CV risk is a key part of T2D disease management [3]