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Medical literature documents that dehydration during GLP-1 therapy increases risk of kidney stress and electrolyte imbalance

doi: 10.3803/EnM.2019.34.3.247 [DOI] [PMC free article] [PubMed] [Google Scholar] 49.Silver HJ Olson D Mayfield D, et al

The discrepant results on BW between the SUSTAIN 7 trial and the present study could be ascribed partially to the differences in the study design
Internal hemorrhoids lie inside the anal canal, where they primarily cause the symptom of intermittent bleeding, usually with bowel movements, and sometimes mucous discharge

Whether the addition of glucagon receptor agonism in retatrutide meaningfully alters the overall GI side effect burden compared with approved agents remains uncertain
