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March 18 Product: Orchard Therapeutics Lenmeldy Indication: Metachromatic leukodystrophy Monday, the FDA gave a glimmer of hope to families of children with metachromatic leukodystrophy (MLD), a rare genetic disease affecting the brain and nervous system, with the approval of Orchard Therapeutics Lenmeldy

Klasen, Claudia Cavelti-Weder, and Tarik Delko have no conflicts of interest or financial ties to disclose

Despite our knowledge of obesity as a treatable, chronic disease, people living with obesity still face many challenges in their health and weight management journey, said Joe Nadglowski, president and chief executive officer of the Obesity Action Coalition

Recommended needle gauge and length for subcutaneous self-injection For subcutaneous injection in the abdomen, thigh or upper arm the route used for all GLP-1 medications UK and European diabetes nursing guidance has converged on shorter, finer needles for almost all adults

Adverse effects can include: Rarely, people using GLP-1 agonists have experienced severe pancreas damage

Potential Interactions and Side Effects Even without direct studies on their combination, we can anticipate potential interactions and exacerbated side effects by examining the known profiles of each drug