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Semaglutide should be given once weekly with no regard to time of day or meals
In addition, activation of GLP-1R regulates mitochondrial over fission by the cAMP/PKA pathway while improving mitochondrial function in A-treated astrocytes and ameliorating pathological lesions in AD (Xie et al., 2021)
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However, the significance of this finding in humans is still unclear, and further research is needed to determine the potential risks in humans
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