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Mounjaro (Tirzepatide): Dual-Action Innovation Mechanism: Targets both GIP and GLP-1 receptors to boost insulin sensitivity and suppress appetite

30 A total of 711 patients with T2DM (mean baseline A1C of approximately 8% in all treatment groups) were enrolled and randomized to receive one of three interventions: 1) 14 mg daily of oral semaglutide

The cardiovascular benefits observed following GLP-1RA treatment could be secondary to improvements in glycemia, blood pressure, postprandial lipidemia, and inflammation

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GLP-1R agonists show great potential in AD, but key challenges, such as blood brain barrier (BBB) penetration, clinical trial inconsistency, long-term safety and precision therapy, need to be addressed