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The reason for this limitation is twofold: first, the body can develop a tolerance to the medication over time, meaning its appetite-suppressing effects may diminish

[DOI] [PubMed] [Google Scholar] 167.Mastaitis J.W., Gomez D., Raya J.G., Li D., Min S., Stec M., Kleiner S., McWilliams T., Altarejos J.Y., Murphy A.J., et al

If you're experiencing hunger before your next weekly dose, contact your PlexusDx provider to discuss dose adjustment or medication alternatives rather than self-adjusting your schedule

But after quitting the drug, they regained 11.6 percentage points of lost weight in a year, bringing their net loss to 5.6 percent over a 120-week period

Small changeslike portion size, meal timing, and food choicescan make a big difference in how you feel and how well the medication works

The slower increase gives your body more time to adjust at each level