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Description
Cryo-electron microscopy studies (Li et al., 2024, Cell Discovery) revealed the peptide adopts a single continuous helix achieving balanced activation through conserved interactions and receptor-specific transmembrane domain contacts
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At up to 80 weeks, the results were comparable to bariatric surgery outcomes, which is remarkable for a medication-based intervention
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STAT5 deletion in the brain causes hyperphagia and obesity [95]
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