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Description
Providers should present realistic expectations about nausea prevalence and duration, discuss strategies for management, and establish clear criteria for dose adjustment or medication switching

[46] It achieves this by activating the AMPK and SIRT1 pathways, which in turn upregulates the expression of uncoupling protein 1 (UCP1)
Head-to-head comparator trials have been conducted, supporting the use of GLP-1 RAs in this role

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2025;14:e240529

doi: 10.1038/s41581-020-0266-9
