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The class of drugs, which includes Novo Nordisks Ozempic and Wegovy, are associated with the risk of gastrointestinal adverse events when used for weight loss, finds a study published Thursday in JAMA.

These medications work by curbing hunger, delaying stomach emptying, and controlling blood sugar levels

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2 Key Trends: The Next Generation Will Compete on Convenience and Potency Formulation Innovation Oral GLP-1 products are emerging as a major frontier, with over 10 oral candidates in development

GLP-1 medications may help address menopause-related weight gain by regulating appetite and metabolism, but individual response depends on hormonal status, metabolic biomarkers, and genetic predispositions

Five scientists won this years Breakthrough Prize in Life Sciences for their work on GLP-1 and the development of drugs for diabetes and obesity.