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Description
Molecular and cellular mechanisms of glucagon-like peptide-1 receptor agonist-mediated attenuation of cardiac fibrosis

GLP-1 RAs are increasingly recommended by current guidelines as preferable treatments in these groups, and our mechanistic studies on inflammatory pathways reinforce and validate these recommendations

Renal elimination of unchanged orforglipron is minimal, suggesting that dose adjustment in patients with renal impairment may not be necessary

The results

Pair that with consistent protein intake, and you have the two most powerful tools for preserving lean mass on a GLP-1
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