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What the 2025 Expert Consensus Found Using a Delphi process with 58 experts from 17 countries, the panel reviewed available evidence and reached key agreements: 1

Binge Eating and Shopping : Anecdotally, some patients report less compulsive eating and even reduced impulsive spending

A 2024 retrospective analysis examined adults with sickle cell disease treated with GLP-1 RAs, demonstrating improvement in estimated glomerular filtration rate (eGFR) slope in 80% of patients receiving GLP-1 RA treatment [183]

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Patients with obesity and HFpEF typically have increased pulmonary vascular resistance and mean pulmonary artery pressure, as well as signs of right ventricular dysfunction

Individuals with Obesity or Overweight: Especially those with weight-related health problems like high blood pressure, high cholesterol, or sleep apnea