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Though the central nervous system and pancreas also produce the hormone in smaller amounts

Evolving data suggest that GLP-1RAs may be the first effective anti-consumption agents with potential applications in reducing food cravings, alcohol consumption, nicotine addiction, recreational drug use, compulsive gambling, and even uncontrollable shopping behaviors

Retatrutide phase 2 obesity trial investigators

The studys results, presented at the European Congress on Obesity in Dublin, found that while 12% of adolescents who were taking the placebo were able to lose enough weight to no longer be classed as clinically obese, for those who were assigned semaglutide, almost 45% of them were able to drop below the clinical definition for obesity

Semaglutide once weekly as add-on to SGLT-2 inhibitor therapy in type 2 diabetes (SUSTAIN 9): A randomised, placebo-controlled trial