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While these drugs offer proven cardiovascular benefits, clinical trials consistently show a modest heart rate increase of 14 beats per minute in most patients

doi: 10.1016/j.gene.2016.05.018 [DOI] [PubMed] [Google Scholar] 165.de la Monte SM, Re E, Longato L, Tong M

Cannabis smoking and diabetes mellitus: results from meta-analysis with eight independent replication samples

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However, women may experience stronger appetite suppression effects and may benefit from slower titration in some cases

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