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Description
In a locomotor activity assay, systemic administration of liraglutide (100 or 200 g/kg, s.c.) dose-dependently reduced cocaine-induced hyperlocomotion (10 mg/kg, i.p.) without altering baseline locomotion
Gastric Band-related side effects also occurred more commonly in the liraglutide arm (L: 15 band-related AEs, P: 5 band-related AEs)
The subcutaneous route also protects the medication itself
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The point here is simply that the receptor offers more than one signaling lever to pull
Regulatory decisions and large-scale clinical evidence are establishing the drug class as a multi-system therapeutic platform
