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Although originally prescribed to treat type 2 diabetes (Ozempic and Mounjaro), semaglutide and tirzepatide are becoming more and more popular for weight loss

Background therapies as adjunct to diet and exercise included metformin (51%), a combination of metformin and insulin (40.1%), insulin (3.2%), or none (5.7%)

GLP-1s are unlikely to deliver therapeutic value when so many individuals stop treatment after two years, but the findings also illustrate the need for obesity care management programs to improve adherence. Prime/MRx has been at the forefront of GLP-1 insights since we released our year-one research, and though we continue to see declines in persistence and adherence, we are committed to providing clients with actionable data and insights that can steer positive health outcomes for individuals. David Lassen, chief clinical officer David Lassen, chief clinical officer While real-world data is central to discussions about affordability and access, especially as the popularity of GLP-1 drugs for weight loss continues to climb, so too are comprehensive management strategies

We have spent the last 18 months reading every GLP-1 lean-mass paper we can find and stress-testing the resulting protocol with our own readers

For a lot of people, the hard part is not convincing a doctor to write the script

Agree on a tapering schedule, monitoring plan, and the specific threshold at which you would restart medication