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Clinical studies in humans have not been published so far ( Development, preclinical, and early clinical data on the GIP/GLP-1 receptor agonist tirzepatide Among the GIP/GLP-1 receptor agonists, tirzepatide (LY3298176) is the compound that is the most advanced in development and the first substance in this class that has received approval for the therapy of T2D by the FDA in May 2022 (manufacturer Eli Lilly Comp., trade name Mounjaro ) (56)

Meta-analysis of the association between body mass index and health-related quality of life among adults, assessed by the SF-36

Medical education initiatives enhance physician training in obesity pharmacotherapy management and patient selection criteria

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Amylin agonism reduces the appetite and food intake and has also glucose-lowering actions by slowing the gastric emptying and suppressing glucagon secretion

However, the baseline weight was similar between groups