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Without estrogens balancing effects, its common to experience a slower metabolic rate, increased fat accumulation, and changes in where fat is stored, often around the midsection

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Seek timely medical care for severe, persistent, or concerning symptoms.

Larger and longer-duration clinical trials are needed to further evaluate the efficacy and safety of GIP receptor and glucagon receptor agonism

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Cardiovascular applications and other metabolic uses contribute a combined share of around 10%, reflecting emerging therapeutic potential
