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Fiber, certain starches, and sulfur-containing amino acids all get processed through bacterial fermentation

Withhold treatment temporarily until the resolution of AEs and then resume treatment

Semaglutide can attenuate inflammation in MASLD by downregulating the IRE1-XBP1-C/EBP (inositol-requiring transmembrane kinase/endonuclease-1-X-box binding protein 1-CCAAT/enhancer binding protein ) pathway in macrophages ( 2 ( 4.1.2 GLP-1RAs regulate the immune cells to protect the liver against fibrosis and neoplasia Exenatide and liraglutide can elevate cAMP levels and reduce the M1/M2 ratio through the cAMP-PKA-STAT3 pathway, resulting in amelioration of injured liver function and liver inflammation (Somm et al., 2021)

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TIMP: tissue inhibitor of MMPs

Lefebvre P, Cariou B, Lien F, Kuipers F, Staels B