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10.1080/00325481.2021.2002616 78 WolfeD.KanjiS.YazdiF.BarbeauP.RiceD.BeckA.et al (2020)

These disorders can be associated with insulin resistance, hyperglycemia-induced damage, oxidative stress, astrocyte abnormalities, and mitochondrial dysfunction, resulting in insufficient energy supply, altered synaptic plasticity, death of neuronal cells, as well as functional and structural damage to reward networks

However, a false positive skin test result is possible given the limitations of skin testing with subcutaneous agents

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