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continued clinical development of oral GLP-1 receptor agonists

SGLT2 inhibitors provide substantial benefits for people with type 2 diabetes mellitus and either established HF or elevated HF risk [86]

The oral DPP4 inhibitors sitagliptin (marketed as Januvia ) and vildagliptin (marketed as Glavus ) have been shown to reduce the overall percentage of HbA 1c by about 0.6-0.7%

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5.4 Gastrointestinal Side Effects and Nutrient Loss Nausea and vomiting are well-documented adverse effects. Persistent vomiting or diarrhoea may: Increase electrolyte loss Reduce caloric intake Reduce dietary diversity However: These effects are typically transient and dose-related

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