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In a study published in JAMA Network Open in January 2025, which included more than 125,000 patients, nearly 65 percent of those taking GLP1s for reasons other than Type 2 diabetes discontinued them within one year

30 Bouchoucha, M., B

Isaacs says that while most people can safely take a GLP-1, you should avoid it if you have severe gastroparesis (stomach paralysis)
