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GLP-1RAs mitigate these adverse impacts by enhancing fatty acid oxidation via the Creb5/NR4a1 signaling axis, thereby reducing mitochondrial damage, lipid accumulation, and ATP deficiency (77, 78, 83)

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The recruited patients are receiving 265 mg ALZ-801 or placebo twice daily for 18 months

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Many find it helpful to set phone reminders or pair their injection with a weekly habit, like meal prepping or watching a favorite show