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A small study of 26 lean, normal-weight men ages 18 to 50 with normal hormone profiles and satisfactory sexual function found no meaningful changes in hormones, sexual desire, or sperm characteristics during GLP-1 use

Retatrutide targets three receptors (GLP-1, GIP, and glucagon), while Ozempic targets only GLP-1

84 In contrast, MPTP treatment reduces TH-positive neurons, decreases concentrations of dopamine as well as its metabolites 3,4-dihydroxyphenylacetic acid and homovanillic acid, and increases the ratio of dopamine metabolites to dopamine

So many of our clients who have previously been stuck in a binge-restrict cycle on our program are satiated and no longer have the urge to binge while eating appropriate overall calories and especially protein

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A 2025 analysis found that GLP-1 agonists given for diabetes were associated with a reduced risk of substance use among hundreds of thousands of United States Veterans and a 2024 examination of over 500k patients 4 Qeadan, F., McCunn, A., & Tingey, B