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But it surely wont be the last, and the competition over the best obesity drug is only likely to heat up in the years to come.
Obese persons are likely responsible for an outsized percentage of sales by volume, and its not uncommon to meet someone with obesity who consumes fast food twice a day
Further, direct stimulation of the GLP-1 receptor on cholangiocytes can lead to enhanced cellular proliferation and an elevated likelihood of cholestasis [47]
Supplements like berberine or curcumin are marketed as ways to boost your body's natural GLP-1 production or mimic its effects, but the reality is that the data behind these claims is limited." This isn't to say that some supplements don't offer any potential benefits
By 4 weeks, GLP-1 receptor mRNA returned to normal levels while the stomach slowing effect disappeared [24]
As GLP-1 therapy improves glucose control, this osmotic effect typically diminishes, potentially normalising previously excessive urination patterns
