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A GLP-1 RA or tirzepatide may be considered as an add-on (to metformin plus an SGLT2 inhibitor) for glycaemic control, if initial therapy is insufficient

The cardiovascular disease continuum validated: clinical evidence of improved patient outcomes: part I: pathophysiology and clinical trial evidence (risk factors through stable coronary artery disease)

Get your baseline

CrossRef Autophagy alterations in obesity, type 2 diabetes, and metabolic dysfunction-associated steatotic liver disease: the evidence from human studies Patrycja Jakubek, Barbara Pakula, Martin Rossmeisl, Paolo Pinton, Alessandro Rimessi, Mariusz Roman Wieckowski Internal and Emergency Medicine.2024

I don't think the way the FDA has done this has been productive. The APC, which represents over 600 compounding pharmacies in the US, has sent a letter to the FDA urging it to use enforcement discretion and allow compounders an extended off-ramp to help transition patients

John Giangrande can relate
